Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1998

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Case-control study of risk of cerebral sinus thrombosis in oral

contraceptive users who are carriers of hereditary prothrombotic conditions.

AUTHORS

de Bruijn SF; Stam J; Koopman MM; Vandenbroucke JP

SOURCE

BMJ (CLINICAL RESEARCH ED.). 1998 Feb 21;316(7131):589-92.

ABSTRACT

The risk of cerebral sinus thrombosis in oral contraceptive (OC) users who are carriers of a hereditary prothrombotic

condition (factor V Leiden mutation, protein C, protein S, or antithrombin deficiency) was investigated in a case-

control study conducted in the Netherlands in 1992-96. Enrolled were 40 cases 18-54 years of age with cerebral

sinus thrombosis recruited from neurologic teaching hospitals throughout the Netherlands and 2248 healthy,

randomly selected community controls 18-49 years old. 34 cases (85%) were using OCs at the time of the sinus

thrombosis and 1007 controls (45%) were current OC users; the odds ratio restricted to women 18-49 years of age

was 13 (95% confidence interval, 5-59). The presence of hereditary coagulation abnormalities was investigated in 36

of the 40 women with thrombosis. 7 of these patients (19%) had a prothrombotic deficiency, while a rate of 7%

would be expectable. In OC users who also carried a prothrombotic defect, the odds ratio for cerebral sinus

thrombosis was 34 compared with women with neither of these risk factors. These findings suggest that the use of

OCs and being a carrier of a hereditary prothrombotic condition increase the risk of and interact in a multiplicative

way in the development of cerebral sinus thrombosis. (PubHealth.info Document ID: CONT1T 4583-06)

PubHealth.info NOTE: The author(s) of this article titled, "Case-control study of risk of cerebral sinus thrombosis in

oral contraceptive users who are carriers of hereditary prothrombotic conditions.", is(are) de Bruijn SF; Stam J;

Koopman MM; Vandenbroucke JP. The source of this article is "BMJ (CLINICAL RESEARCH ED.). 1998 Feb

21;316(7131):589-92.". This article was published in 1998 in English language(s). (PubHealth.info® Document ID:

CONT1T 4583-06. All rights reserved with PubHealth.info) PIN: 4583

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