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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "ABORTION". An abortion is the removal or expulsion of an embryo or fetus from the uterus, resulting in or caused by its death. This can occur spontaneously as a miscarriage, or be artificially induced by chemical, surgical or other means. Commonly, "abortion" refers to an induced procedure at any point during pregnancy; medically, it is defined as miscarriage or induced termination before twenty weeks' gestation, which is considered nonviable.





YEAR: 2001




CATEGORY: Abortion



TITLE



Complete, early abortion with misoprostol. [Aborto temprano y completo con

misoprostol.]



AUTHORS


SOURCE

Reproductive Health Matters. 2001 Nov;9(18):190.



ABSTRACT

The drug misoprostol (Cytotec) has been used to induce medical abortion both alone and in combination with

mifepristone. Misoprostol is inexpensive, already licensed in many countries as a treatment for stomach ulcers and

does not need to be refrigerated. Studies are ongoing in an effort to refine the dosage, to increase rates of complete

abortion in early pregnancy and decrease side effects, e.g., vaginal insertion of misoprostol has been tested for

doses ranging between 200 and 800 mcg. In this trial, conducted in Cuba, the dosage used was 1000 mcg, in order

to increase the strength of uterine contractions. 300 women between 42 and 63 days of pregnancy who wanted to

terminate their pregnancies were trained to insert 5 200-mcg tablets of misoprostol into the vagina. They were also

given medication to alleviate the side effects of nausea, pelvic pain, cramping, and diarrhea. If abortion had not

occurred after 24 hours, the women repeated the regimen. If abortion still did not occur, the regimen was repeated

again 24 hours later. All women who aborted then received an additional dose of 600 mcg of misoprostol vaginally

24 hours after ultrasound confirmation that abortion had occurred, to ensure complete yterine evacuation. Complete

abortion occurred in 93% of cases. With 1000 mcg of misoprostol cramping began after 3 hours, bleeding at 5

hours, and expulsion at 8 hours. A post study questionnaire showed that the majority of women felt positively about

the procedure and 94% said they would use the procedure again in future if the need arose. Although side effects

such as pain and nausea were common, they could be alleviated with medication. This regimen of misoprostol

seems acceptable and effective for early termination of pregnancy. (PubHealth.info Document ID: ABOR1T 894-06)



PubHealth.info NOTE: The author(s) of this article titled, "Complete, early abortion with misoprostol. [Aborto

temprano y completo con misoprostol.]", is(are) . The source of this article is "Reproductive Health Matters. 2001

Nov;9(18):190.". This article was published in 2001 in English language(s). (PubHealth.info® Document ID: ABOR1T

894-06. All rights reserved with PubHealth.info) PIN: 894




 

 

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